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Cd84−/− mice are protected after transient middle cerebral artery occlusion (tMCAO).
A, Representative triphenyltetrazolium chloride–stained 2-mm brain slices from 1 WT and 1 Cd84−/− mouse 24 h after tMCAO. Bar=1 cm. B, Infarct volumes 24 h after tMCAO of WT (n=16) and Cd84−/− mice (n=18; P=0.0198). C, WT (n=18) and Cd84−/− (n=21) neuroscore at 24 h after tMCAO (P=0.0269). Statistical significances analyzed by Mann-Whitney U test. *P<0.05.
