Table 2. Neuropsychological performance from baseline (T1) and retest (T2) between genetic groups.
Measure | Variable | Mean T1 | Mean T2 | Δ | p value |
---|---|---|---|---|---|
ACE | Total ε3ε3 | 94.67 ± 3.67 | 93.70 ± 4.88 | -.97 ± 5.33 | 0.06 (t = 1.903) |
Total ε3ε4 | 92.96 ± 3.82 | 94.37 ± 2.31 | 1.41 ± 3.35 | ||
Memory ε3ε3 | 24.70 ± 1.92 | 24.97 ± 1.43 | .27 ± 2.13 | 0.03 (t = 2.120) | |
Memory ε3ε4 | 23.70 ± 1.66 | 25.00 ± 1.07 | 1.26 ± 1.75 | ||
Visuospatial ε3ε3 | 14.93 ± 1.05 | 14.20 ± 1.32 | -.73 ± 1.34 | 0.60 (t = 0.523) | |
Visuospatial ε3ε4 | 14.85 ± 1.21 | 14.15 ± .94 | -.70 ± .99 | ||
ROCF | Copy 3ε3 | 33.23 ± 2.77 | 32.75 ± 2.84 | -.38 ± 2.91 | 0.88 (t = 0.145) |
Copy ε3ε4 | 32.28 ± 2.62 | 32.15 ± 2.57 | -.18 ± 2.87 | ||
Recall ε3ε3 | 20.51 ± 6.32 | 21.83 ± 5.34 | 1.06 ± 4.73 | 0.13 (t = 1.516) | |
Recall ε3ε4 | 18.15 ± 6.11 | 21.50 ± 5.02 | 2.60 ± 7.68 | ||
CCI | Episodic ε3ε3 | 19.28 ± 6.46 | 18.40 ± 6.29 | .39 ± 4.12 | 0.38 (t = -0.87) |
Episodic ε3ε4 | 21.48 ± 6.76 | 22.36 ± 6.44 | -.96 ± 5.42 | ||
EF ε3ε3 | 11.47 ± 4.53 | 10.45 ± 3.77 | .64 ± 3.12 | 0.02 (t = -2.244) | |
EF ε3ε4 | 11.56 ± 3.75 | 12.75 ± 4.37 | -1.22 + 2.53 |
ACE = The Addenbrooke’s cognitive examination; ROCF = Rey-Osterrieth complex figure test; CCI = Cognitive change index; EF; Executive function; T1 = Baseline; T2 = retest; Δ change/difference = T2 value—T1 value; p value = significant change between genetic groups.