Skip to main content
. 2020 Sep 22;15(9):e0239077. doi: 10.1371/journal.pone.0239077

Table 2. Neuropsychological performance from baseline (T1) and retest (T2) between genetic groups.

Measure Variable Mean T1 Mean T2 Δ p value
ACE Total ε3ε3 94.67 ± 3.67 93.70 ± 4.88 -.97 ± 5.33 0.06 (t = 1.903)
Total ε3ε4 92.96 ± 3.82 94.37 ± 2.31 1.41 ± 3.35
Memory ε3ε3 24.70 ± 1.92 24.97 ± 1.43 .27 ± 2.13 0.03 (t = 2.120)
Memory ε3ε4 23.70 ± 1.66 25.00 ± 1.07 1.26 ± 1.75
Visuospatial ε3ε3 14.93 ± 1.05 14.20 ± 1.32 -.73 ± 1.34 0.60 (t = 0.523)
Visuospatial ε3ε4 14.85 ± 1.21 14.15 ± .94 -.70 ± .99
ROCF Copy 3ε3 33.23 ± 2.77 32.75 ± 2.84 -.38 ± 2.91 0.88 (t = 0.145)
Copy ε3ε4 32.28 ± 2.62 32.15 ± 2.57 -.18 ± 2.87
Recall ε3ε3 20.51 ± 6.32 21.83 ± 5.34 1.06 ± 4.73 0.13 (t = 1.516)
Recall ε3ε4 18.15 ± 6.11 21.50 ± 5.02 2.60 ± 7.68
CCI Episodic ε3ε3 19.28 ± 6.46 18.40 ± 6.29 .39 ± 4.12 0.38 (t = -0.87)
Episodic ε3ε4 21.48 ± 6.76 22.36 ± 6.44 -.96 ± 5.42
EF ε3ε3 11.47 ± 4.53 10.45 ± 3.77 .64 ± 3.12 0.02 (t = -2.244)
EF ε3ε4 11.56 ± 3.75 12.75 ± 4.37 -1.22 + 2.53

ACE = The Addenbrooke’s cognitive examination; ROCF = Rey-Osterrieth complex figure test; CCI = Cognitive change index; EF; Executive function; T1 = Baseline; T2 = retest; Δ change/difference = T2 value—T1 value; p value = significant change between genetic groups.