Table 7. Cox models for death and death or intubation by type of glucocorticoid therapy.
Death | Death or intubation | |||||||
---|---|---|---|---|---|---|---|---|
Whole cohort | SpO2/FiO2 ≤353 | Whole cohort | SpO2/FiO2 ≤353 | |||||
HR (95%CI)* | p | HR (95%CI)* | p | HR (95%CI)** | p | HR (95%CI)** | p | |
Week-2-MP | reference | reference | reference | reference | ||||
Non-pulse glucocorticoids | 10.09 (2.14–47.50) | 0.003 | 16.20 (1.86–141.05) | 0.012 | 13.71 (3.76–50.07) | <0.001 | 15.50 (3.14–76.38) | 0.001 |
Out-of-week-2-MP | 5.04 (0.91–27.86) | 0.064 | 9.83 (0.78–12.41) | 0.044 | 7.38 (1.86–29.29) | 0.004 | 9.72 (1.91–49.31) | 0.006 |
No glucocorticoids | 4.14 (0.81–21.23) | 0.088 | 7.04 (0.78–63.71) | 0.082 | 3.58 (0.89–14.32) | 0.072 | 5.07 (1.00–25.67) | 0.050 |
MP: methyl-prednisolone pulses; Week-2-MP: methyl-prednisolone pulses in week 2. HR: hazard ratio; CI: confidence interval.
*Model adjusted by hypertension, SaO2FiO2 and Curb65 score.
**Model adjusted by SaO2FiO2 and Curb65 score.