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. 2020 Sep 22;15(9):e0239401. doi: 10.1371/journal.pone.0239401

Table 7. Cox models for death and death or intubation by type of glucocorticoid therapy.

Death Death or intubation
Whole cohort SpO2/FiO2 ≤353 Whole cohort SpO2/FiO2 ≤353
HR (95%CI)* p HR (95%CI)* p HR (95%CI)** p HR (95%CI)** p
Week-2-MP reference reference reference reference
Non-pulse glucocorticoids 10.09 (2.14–47.50) 0.003 16.20 (1.86–141.05) 0.012 13.71 (3.76–50.07) <0.001 15.50 (3.14–76.38) 0.001
Out-of-week-2-MP 5.04 (0.91–27.86) 0.064 9.83 (0.78–12.41) 0.044 7.38 (1.86–29.29) 0.004 9.72 (1.91–49.31) 0.006
No glucocorticoids 4.14 (0.81–21.23) 0.088 7.04 (0.78–63.71) 0.082 3.58 (0.89–14.32) 0.072 5.07 (1.00–25.67) 0.050

MP: methyl-prednisolone pulses; Week-2-MP: methyl-prednisolone pulses in week 2. HR: hazard ratio; CI: confidence interval.

*Model adjusted by hypertension, SaO2FiO2 and Curb65 score.

**Model adjusted by SaO2FiO2 and Curb65 score.