TABLE 2.
APOE ε4 on rsFC DMN subsystems across race/ethnicity
| 95% CI | |||
|---|---|---|---|
| B(SE) | Lower | Upper | |
| Frontal DMN | |||
| Age | 0.0002(.0002) | –0.0002 | .001 |
| Sex/Gender | .003(.003) | –.002 | .009 |
| Scan Protocol | .031(.003) | .025 | .037 † |
| APOE ε4+ | –.001(.006) | –.013 | .010 |
| Hispanic | –.005(.004) | –.013 | .003 |
| NH Black | –.0004(.005) | –.009 | .009 |
| Hispanic x APOE ε4+ | .001(.008) | –.015 | .017 |
| NH Black x APOE ε4+ | –.001(.008) | –.016 | .014 |
| Temporal DMN | |||
| Age | 0.0002(.0003) | –0.0003 | .001 |
| Sex/Gender | .001(.004) | –.006 | .008 |
| Scan protocol | .026(.004) | .019 | .033 † |
| APOE ε4+ | –.010(.007) | –.023 | .003 |
| Hispanic | –.007(.005) | –.016 | .003 |
| NH Black | –.012(.005) | –.022 | –.001* |
| Hispanic x APOE ε4+ | .011(.010) | –.008 | .030 |
| NH Black x APOE ε4+ | .024(.009) | .006 | .041 ^ |
| Occipito‐parietal DMN | |||
| Age | –0.00002(.0004) | –.001 | .001 |
| Sex/Gender | –0.002(.005) | –.010 | .008 |
| Scan protocol | .062(.005) | .052 | .072† |
| APOE ε4+ | –.002(.010) | –.021 | .017 |
| Hispanic | –.009(.007) | –.023 | .004 |
| NH Black | –.020(.008) | –.035 | –.005 ^ |
| Hispanic x APOE ε4+ | .015(.014) | –.011 | .042 |
| NH Black x APOE ε4+ | .006(.013) | –.019 | .031 |
Abbreviations: APOE, apolipoprotein E; B, unstandardized parameter estimate; CI, confidence interval; DMN, default mode network; NH, non‐Hispanic; SE, standard error.
Note: Underlined significant findings did not survive Bonferroni correction.
*
P < .05.
^
P < .01.
†
P < .001.