Table 5.
The influence of high degree of protocol compliance on inflammation and postoperative surgical outcomes
| Variable | HCR (n = 59, 72%) | LCR (n = 12, 14.6%) | P-value |
|---|---|---|---|
| Inflammatory marker | |||
| Postoperative WBC count (× 109/L) | 0.976 | ||
| < 10,000 | 31 (52.5) | 6 (50.0) | |
| ≥ 10,000 | 28 (47.5) | 6 (50.0) | |
| Time for WBC count to decrease < 10,000/mm3 (day) | 0.998 | ||
| < 1 | 31 (52.5) | 6 (50.0) | |
| 1–3 | 17 (28.8) | 4 (33.3) | |
| ≥ 4 | 11 (18.6) | 2 (16.7) | |
| Preoperative monocyte count (%) | 0.476 | ||
| ≤9 | 40 (67.8) | 7 (58.3) | |
| >9 | 19 (32.2) | 5 (41.7) | |
| Postoperative monocyte count (%) | 0.015 | ||
| ≤9 | 51 (86.4) | 6 (50.0) | |
| >9 | 8 (13.6) | 6 (50.0) | |
| Postoperative CRP level (mg/L) | 0.657 | ||
| ≤ 0.5 | 42 (71.2) | 7 (58.3) | |
| > 0.5 | 17 (28.8) | 5 (41.7) | |
| Postoperative Glasgow prognostic score | 0.099 | ||
| 0 | 29 (49.2) | 4 (33.3) | |
| 1 | 24 (40.7) | 5 (41.7) | |
| 2 | 6 (10.2) | 3 (25.0) | |
| Postoperative surgical outcome | |||
| Complication | 0.008 | ||
| Yes | 4 (6.8) | 4 (33.3) | |
| No | 55 (93.2) | 8 (66.7) | |
| Clavien-Dindo classification | 0.018 | ||
| Grade I, II | 2 (3.4) | 3 (25.0) | |
| Grade > II | 2 (3.4) | 1 (8.3) | |
| Length of hospital stay (day) | 5.4 ± 1.6 | 9.9 ± 6.0 | < 0.001a |
aValues are presented as number (%) or mean±standard deviation.
HCR, high compliance response; LCR, low compliance response; WBC, white blood cells, CRP, C-reactive protein.
a
Mann-Whitney U-tests.