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. 2020 Sep 21;64(10):e01178-20. doi: 10.1128/AAC.01178-20

FIG 1.

FIG 1

Lung CFU counts in C3HeB/FeJ mice after treatment with BPa with or without L at differing doses and dosing frequencies. (A) Comparison of BPa with or without at L at 45 mg/kg once a day (q.d.), 90 mg/kg q.o.d., or 90 mg/kg q.d. after 2 months of treatment in HN878-infected mice in experiment 1. (B) Comparison of BPa with or without at L at 25 mg/kg q.d., 50 mg/kg q.d., or 100 mg/kg q.d. after 1 month of treatment in H37Rv-infected mice in experiment 2. Abbreviations: B, bedaquiline; Pa, pretomanid; L, linezolid; m, month; q.d., once a day (5/7). Doses used were as follows: 25 mg/kg B q.d., 50 mg/kg Pa (A) or 100 mg/kg Pa q.d. (B). *, P < 0.05. Dark horizontal bars indicate the median value for each group.