TABLE 2.

Lung CFU counts assessed during treatment and proportions of mice relapsing after treatment of BALB/c mice infected with M. tuberculosis HN878

Regimena	Mean lung log10 CFU count ± SD by time pointb
	D-14	D0	M1	M2
Untreated	2.95 ± 0.05	6.48 ± 0.06
BPa			2.33 ± 0.23c	0 ± 0
BPaL45q.d.			2.52 ± 0.12d	0.24 ± 0.54
BPaL90q.o.d.			2.64 ± 0.09e,f	0.31 ± 0.43
1BPaL90q.d./BPa			2.95 ± 0.21g	0.52 ± 0.49
1BPaL90q.d./BPaL90q.o.d.				0.31 ± 0.43
BPaL90q.d.				0.33 ± 0.66

^aFor regimens with two phases, the phases are separated by a slash and the number at the beginning indicates the duration of the initial phase in months. For treatment arms that received the same treatment up to M1 or M2, mice were sacrificed from only one of those arms and used to represent all of the arms receiving the same treatment up to that time point.

^bTime points are shown as days (D-14 or D0) or months (M1 or M2).

^cIndicates a significant difference compared with BPaL_90q.d. with a P value of <0.001.

^dIndicates a significant difference compared with BPaL_90q.d. with a P value of <0.01.

^eIndicates a significant difference compared with BPa with a P value of <0.05.

^fIndicates a significant difference compared with BPaL_90q.d. with a P value of <0.05.

^gIndicates a significant difference compared with BPa with a P value of <0.001.