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. 2020 Sep 21;64(10):e00904-20. doi: 10.1128/AAC.00904-20

TABLE 2.

The MICs and mutations of non-wild-type A. fumigatus isolates from Chinaa

Strain no. Date of sample collection (day/mo/yr) Location of sampling sites MIC (mg/liter)
 cyp51A mutations
VRC ITZ POC
H-13 18/06/2014 ZPPH 1 16 0.5 TR34/L98H/S297T/F495I
H-20 12/07/2014 HCH 1 8 0.125 TR34/L98H/S297T/F495I
H-58 02/03/2016 ZPPH 16 4 1 TR46/Y121F/T289A
H-90 02/03/2016 ZPPH 2 0.5 0.125 None
H-102 02/03/2016 ZPPH 2 0.5 0.25 None
H-197 02/03/2016 ZPPH 2 0.125 0.0625 None
H-85 02/03/2016 AHFPH 8 4 0.5 G448S
H-96 02/03/2016 AHFPH 4 0.5 0.125 G448S
H-98 02/03/2016 AHFPH 8 2 1 G448S
H-103 02/03/2016 AHFPH 8 2 0.5 G448S
H-107 02/03/2016 AHFPH 8 2 0.5 G448S
H-111 02/03/2016 AHFPH 8 2 0.5 G448S
H-114 27/03/2016 ZPTCM 8 2 0.5 G448S
H-120 27/03/2016 ZPTCM 8 1 0.5 G448S
H-126 27/03/2016 ZPTCM 8 2 0.5 G448S
H-149 04/03/2018 ZPPH 2 0.5 0.0625 None
H-152 04/03/2018 ZPPH 2 0.5 0.0625 None
H-161 04/03/2018 ZPPH 2 0.5 0.0625 None
H-190 04/03/2018 ZPPH >16 16 0.25 TR46/Y121F/T289A
H-202 04/03/2018 ZPPH 8 >16 1 TR34/L98H
H-247 04/03/2018 ZPPH 8 4 0.125 F46Y/G89G/M172V/N248T/D255E/L358L/E427K/C454C
H-234 26/03/2018 HCH >16 1 1 TR46/Y121F/T289A
H-237 26/03/2018 HCH 4 0.25 0.0625 None
H-264 26/03/2018 HCH 4 >16 1 TR34/L98H/S297T/F495I
H-176 04/03/2018 TFHZP 2 0.25 0.0625 None
H-184 04/03/2018 TFHZP 2 0.25 0.0625 None
H-186 04/03/2018 TFHZP 2 0.125 0.0625 None
H-191 04/03/2018 TFHZP 2 0.25 0.0625 None
H-197 04/03/2018 TFHZP 2 0.125 0.0625 None
H-206 04/03/2018 TFHZP 2 0.125 0.0625 None
H-208 04/03/2018 TFHZP 4 0.5 0.0625 G170G
H-248 04/03/2018 AHFPH 2 0.5 0.0625 None
H-252 04/03/2018 AHFPH 2 0.25 0.0625 None
H-256 04/03/2018 AHFPH 2 0.5 0.25 None
H-258 04/03/2018 AHFPH 4 0.25 0.125 None
H-218 04/03/2018 AHFPH 2 0.5 0.0625 None
H-242 26/03/2018 ZPTCM >16 0.5 0.5 TR46/Y121F/T289A
H-244 26/03/2018 ZPTCM >16 16 0.25 TR46/Y121F/T289A
H-260 26/03/2018 ZPTCM 2 0.25 0.0625 None
H-261 26/03/2018 ZPTCM 2 0.125 0.0625 None
H-266 26/03/2018 ZPTCM 2 0.125 0.0625 None
H-259 26/03/2018 HTH 4 >16 0.5 TR34/L98H
H-263 26/03/2018 HTH 4 >16 1 TR34/L98H
H-272 01/05/2018 THZP 2 >16 1 TR34/L98H/S297T/F495I
H-277 01/05/2018 THZP 2 0.5 0.0625 None
H-280 01/05/2018 THZP 2 >16 1 TR34/L98H/S297T/F495I
a

ZPPH, Zhejiang Provincial People’s Hospital; HCH, Hangzhou Children’s Hospital; AHFPH, Affiliated Hangzhou First People’s Hospital, Zhejiang University School of Medicine; ZPTCM, Zhejiang Provincial Hospital of TCM; HTH, Hangzhou Third Hospital; THZP, Tongde Hospital of Zhejiang Province; TFHZP, The First Hospital of Zhejiang Province.