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. Author manuscript; available in PMC: 2021 Sep 1.
Published in final edited form as: Exp Hematol. 2020 Aug 2;89:43–54.e2. doi: 10.1016/j.exphem.2020.07.011

Figure 1. Schematic of alternate responses to anemia.

Figure 1.

Left, steady state erythropoiesis is increased by increased levels of erythropoietin (Epo). Right, Inflammation compromises steady state erythropoiesis, which leads to activation of the BMP4 dependent stress erythropoiesis pathway. MPP-multipotential progenitors, CMP- common myeloid progenitor, MEP-megakaryocyte erythroid progenitor, GMP- granulocyte macrophage progenitor, BFU-e- burst-forming units- erythroid, CFU-E- colony forming units-erythroid. The megakaryocyte pathway is not shown in order to simplify the diagram.