Table 2.

Temporal Trends in Infant Mortality Resulting From CHD, by CHD lesion, 1999–2017

Defect	Deaths in all age groups	Deaths during infancy	% deaths that occur during infancy	99–17 AAPC in infant mortality (95% CI)	Among all CHD-related deaths		Excluding infants aged < 1 year
Defect	Deaths in all age groups	Deaths during infancy	% deaths that occur during infancy	99–17 AAPC in infant mortality (95% CI)	Median Age at Death 1999–2006	Median Age at Death 2007–2017	Median Age at Death 1999–2006	Median Age at Death 2007–2017
Anomalous pulmonary venous connection	661	591	89.4	−1.0 (−2.8, 0.9)	30 days	30 days	1 year	34 years
Aortic valve anomalies	946	449	47.5	−4.9 (−6.5, −3.2)	152 days	23 years	45 years	58 years
Atrioventricular septal defect	1033	606	58.7	0.6 (−2.5, 3.8)	183 days	213 days	22 years	32 years
Coarctation of the aorta	898	517	57.6	−3.2 (−5.0, −1.3)	61 days	152 days	38 years	41 years
Common truncus	796	619	77.8	−1.9 (−5.1, 1.4)	30 days	30 days	22 years	19 years
Common ventricle/double inlet ventricle	482	260	53.9	−3.5 (−5.2, −1.7)	183 days	335 days	17 years	18 years
Ebstein anomaly	850	485	57.1	−1.7 (−2.7, −0.6)	30 days	91 days	41 years	48 years
Hypoplastic left heart syndrome	6536	5626	86.1	−2.8 (−3.6, −1.9)	14 days	30 days	2 years	4 years
Pulmonary artery atresia/stenosis	1493	855	57.3	−1.6 (−2.9, −0.3)	183 days	213 days	29 years	35 years
Pulmonary valve anomalies	172	128	74.4	0.7 (−2.7, 4.2)	30 days	61 days	27 years	33 years
Tetralogy of Fallot	3103	1176	37.9	−0.9 (−3.2, 1.5)	8 years	16 years	34 years	38 years
Transposition of the great arteries	2165	1243	57.4	−3.1 (−4.3, −2.0)	61 days	213 days	23 years	30 years
Tricuspid valve anomalies	439	165	37.6	−2.2 (−5.7, 1.5)	12 years	17 years	23 years	31 years
Ventricular septal defect	2613	592	22.7	−5.6 (−7.5, −3.7)	44 years	51 years	60 years	61 years
Other specified congenital heart disease	10900	2311	21.2	−2.0 (−2.8, −1.2)	36 years	39 years	44 years	47 years
Unspecified congenital heart disease	20663	11134	53.9	−1.9 (−2.3, −1.4)	213 days	244 days	26 years	30 years

Footnote: AAPC, average annual percent change; CI, confidence interval

Only deaths in which the CHD is listed as the underlying cause of death are included in this table.

Median age at death is calculated among all cases, not just deaths during infancy. Expressed in days when less than 1 year, otherwise expressed in years.