Table 4.
Neuropsychiatric test measures (mean (SD)) by discriminant analysis dementia prediction status. False Negatives (FN), False Positives (FP), and True Positives (TP) compared individually to True Negatives (TN).
| Domain | Characteristic or Neuropsychological test | Description / Reference | TN (n=512) | FN (n=18) | FP (n=113) | TP (n=42) |
|---|---|---|---|---|---|---|
| Delayed recall | Selective Reminding, Delayed | SelRem Recall, Reproduction | 8.8 (1.4) | 8.6 (1.9) | 7.9 (2.5)* | 6.6 (3.2)* |
| Incidental memory, delayed | BNT, Delayed | Boston, Delayed Recall | 8.0 (3.3) | 7.6 (4.4) | 7.0 (3.9)* | 5.1 (3.8)* |
| Visuospatial Perception | NES2, Pattern Recognition, Correct | Pattern Recognition - No. Correct | 24.2 (1.3) | 24.4 (1.5) | 24.3 (1.1) | 24.4 (0.9) |
| Delayed recall | Face Reproduction | Face Reproduction Total, RT For Correct Responses | 3687.9 (1396.1) | 3840 (1508.1) | 4823.2 (2268.9)* | 5087.7 (2494.1)* |
| Face Reproduction Total, SD For Correct Responses | 2154.9 (1199.3) | 2460.3 (1400.3) | 3117.4 (1565.5)* | 3271.5 (1694.2)* | ||
| Verbal comprehension | BNT, no Cues | Correct without cue | 17.6 (5.6) | 16.5 (5.8) | 15.8 (6.1)* | 14.6 (5.1)* |
| BNT, with Cues | Correct with stim. & phon. cue | 24.0 (4.4) | 22.9 (4.4) | 22.6 (5.0)* | 22.0 (4.2)* | |
| Non-verbal reasoning | Raven Coloured Progressive Matrices | Raven Coloured Progressive Matrices A+B | 17.3 (2.8) | 17.2 (3.1) | 17.2 (2.9) | 16.4 (2.8)* |
| Perceptual Speed | NES2, Pattern Recognition, time | Pattern Recognition - No. Correct RT | 7.6 (2.8) | 7.5 (1.5) | 8.4 (3.1)* | 9.1 (4.4)* |
| Attention, Speed | NES2, Continuous Performance Test with letters | CPT, Mean of RTs for Blocks 1 - 5 | 457.3 (67) | 442.4 (49.8) | 464.2 (60.4) | 479.6 (65.3)* |
| CPT, Std. Deviation of RTs for Blocks 1 - 5 | 87.1 (25.2) | 81.1 (17.9) | 79.8 (24.4)* | 94.2 (25.9)* | ||
| Attention, Speed | NES2, Symbol Digit Modalities Test | Symbol-Digit- Mean for 40 Responses, Seconds | 5.1 (1.6) | 5.5 (1.3) | 5.9 (2.6)* | 6.5 (3)* |
| Symbol-Digit- SD for 40 Responses | 2.6 (1.3) | 2.9 (1.4) | 3.1 (1.9)* | 3.4 (2.1)* | ||
| Speed of processing | Face Recognition Memory Test, Immediate Time | Face Immediate Total RT For Correct Responses | 4224.2 (1810.1) | 3968.3 (1500.8) | 5520.7 (2682.7)* | 6114.8 (2854.5)* |
| Face Immediate Total SD for Correct Responses | 2444.9 (1472.6) | 2402.2 (1395.2) | 3494.5 (1841.4)* | 3807.7 (1958.1)* | ||
| Immediate memory | Selective Reminding, immediate recall | SelRem Recall, Trial 1 | 4.2 (1.2) | 4.2 (1.1) | 3.9 (1.3) | 3.8 (1.2)** |
| Learning and recall | Selective Reminding, Reminders | SelRem Reminders Total | 19.5 (10.8) | 23.4 (11.6) | 26.2 (15.8)* | 30.4 (16.8)* |
| Immediate memory | Face Recognition Memory Test, Immediate recall | Face Immediate - Total No. Correct | 40 (4.9) | 39.3 (7.5) | 38.1 (6.1)* | 37 (6.7)* |
| Delayed recall | Face Recognition Memory Test, Delayed | Face Reproduction Total - No. Correct | 37.1 (5.1) | 37.9 (5.8) | 35.4 (5.7)* | 34.7 (6.1)* |
| Manual motor speed | NES2, Finger Tapping Test, Dominant | No. Taps with Preferred Hand on Best Trial | 69.3 (13.8) | 71.7 (14.9) | 66.4 (13.1)* | 64 (11)* |
| No. Taps with Non-preferred Hand on Best Trial | 64.3 (12.6) | 65.2 (10.7) | 62.2 (11.7) | 58.5 (11.7)* | ||
| No. Taps with Alternating Hands on Best Trial | 79 (19.9) | 81.3 (15.4) | 80.7 (17.2) | 73.2 (17.6) | ||
| Manual motor speed | Purdue Peg Board | Greatest of 3 Trials w. Right Hand | 13.9 (1.9) | 14.1 (1.8) | 14 (1.9) | 13.5 (2.2) |
| Greatest of 3 Trials w. Left Hand | 12.9 (2) | 13 (2.3) | 13.1 (2) | 12.4 (2.3) | ||
| Greatest of 3 Trials w. Both Hands | 10.2 (1.7) | 10.2 (1.4) | 10.4 (1.7) | 9.9 (2) | ||