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. 2020 Sep 22;11:4796. doi: 10.1038/s41467-020-18367-y

Table 3.

Genome-wide significant associations (pDiscovery < 1.09 × 10−9) of global and regional CV.

Lobe Region Locus Position Lead SNP Nearest gene Annotation N pDiscovery
Global 6q22.32 126792095 rs11759026 MIR588 Intergenic 22,410 6.31E−19
17q21.31 44790203 rs169201 NSF Intronic 22,784 2.11E−13
17q21.32 43549608 rs149366495 PLEKHM1 Intronic 22,099 8.18E−13
12q14.3 66358347 rs1042725 HMGA2 3’UTR 22,784 7.04E−11
12q23.2 102921296 rs11111293 IGF1 Intergenic 22,784 5.45E−10
6q22 109002042 rs4945816 FOXO3 3’UTR 22,784 8.93E−10
Frontal Superior frontal 5q14.3 92186429 rs888814 NR2F1-AS1 Intergenic 22,692 3.29E−13
Rostral middle frontal 15q14 39636227 rs17694988 C15orf54 Intergenic 22,793 3.15E−11
Caudal middle frontal 2q12.1 105460333 rs745249 LINC01158 ncRNA_intronic 22,726 2.35E−11
6q22.32 127068983 rs853974 RSPO3 Intergenic 22,351 4.82E−11
Pars opercularis 5q23.3 128734008 rs12187568 ADAMTS19 Intergenic 20,753 4.27E−18
15q14 39639898 rs4924345 C15orf54 Intergenic 22,758 1.97E−14
Pars triangularis 3q24 147106319 rs2279829 ZIC4 UTR3 22,759 3.16E−23
7q21.3 96196906 rs67055449 LOC100506136 Intergenic 22,759 4.03E−19
15q14 39633904 rs2033939 C15orf54 Intergenic 22,759 8.49E−14
7q21.3 96129071 rs62470042 C7orf76 Intronic 22,759 7.38E−13
6q15 91942761 rs12660096 MAP3K7 Intergenic 22,759 4.74E−10
Lateral orbitofrontal 14q22.2 54769839 rs6572946 CDKN3 Intergenic 22,801 2.29E−10
Precentral 15q14 39634222 rs1080066 C15orf54 Intergenic 22,699 5.84E−125
10q25.3 118648841 rs3781566 SHTN1 Intronic 22,699 4.68E−11
Temporal Superior temporal 3q26.32 177296448 rs13084960 LINC00578 ncRNA_intronic 22,681 1.12E−11
Banksts 14q23.1 59072226 rs186347 KIAA0586 Intergenic 22,727 1.15E−15
Fusiform 14q23.1 59833172 rs1547199 DAAM1 Intronic 22,605 4.58E−10
1p33 47980916 rs6658111 FOXD2 Intergenic 22,605 7.78E−10
Transverse temporal 2q23.2 150012936 rs2046268 LYPD6B Intronic 22,786 2.55E−12
Parahippocampal 2q33.1 199809716 rs966744 SATB2 Intergenic 22,747 2.23E−10
Parietal Superior parietal 15q14 39633904 rs2033939 C15orf54 Intergenic 22,723 4.28E−23
16q24.2 87225139 rs4843227 LOC101928708 Intergenic 22,723 1.16E−13
19p13.2 13109763 rs68175985 NFIX Intronic 21,777 3.27E−11
5q15 92866553 rs62369942 NR2F1-AS1 ncRNA_intronic 21,664 4.32E−10
Inferior parietal 20q13.2 52448936 rs6097618 SUMO1P1 Intergenic 22,701 2.09E−17
12q14.3 65797096 rs2336713 MSRB3 Intronic 22,701 2.47E−13
3q13.11 104724634 rs971551 ALCAM Intergenic 22,701 2.34E−10
Supramarginal 15q14 39632013 rs71471500 THBS1 Intergenic 22,645 9.71E−28
14q23.1 59627631 rs2164950 DAAM1 Intergenic 22,645 3.59E−20
3q24 147106319 rs2279829 ZIC4 UTR3 22,645 5.36E−18
Postcentral 15q14 39633904 rs2033939 THBS1 Intergenic 22,662 4.34E−133
3q24 147106319 rs2279829 ZIC4 UTR3 22,662 2.54E−17
9q21.13 76144318 rs67286026 ANXA1 Intergenic 22,662 5.03E−11
2q36.3 226563259 rs16866701 NYAP2 Intergenic 22,545 5.69E−11
Precuneus 14q23.1 59628609 rs74826997 DAAM1 Intergenic 22,803 4.85E−20
3q28 190663557 rs35055419 OSTN Intergenic 22,428 2.02E−10
2p22.2 37818236 rs2215605 CDC42EP3 Intergenic 22,803 3.43E−10
3q13.11 104713881 rs12495603 ALCAM Intergenic 22,803 9.71E−10
Occipital Lateral occipital 14q23.1 59627631 rs2164950 DAAM1 Intergenic 22,799 6.89E−16
Lingual 14q23.1 59625997 rs73313052 DAAM1 Intergenic 22,805 1.06E−20
6q22.32 127089401 rs2223739 RSPO3 Intergenic 22,805 1.75E−10
Cuneus 14q23.1 59625997 rs73313052 DAAM1 Intergenic 22,799 4.59E−43
11p15.3 12072213 rs11022131 DKK3 Intergenic 22,799 5.96E−12
13q31.1 80192236 rs9545156 LINC01068 Intergenic 22,799 4.09E−10
Pericalcarine 14q23.1 59628679 rs76341705 DAAM1 Intergenic 22,824 1.39E−29
13q31.1 80191873 rs9545155 LINC01068 intergenic 22,824 2.25E−13
11p14.1 30876113 rs273594 DCDC5 Intergenic 22,824 3.51E−13
1p13.2 113208039 rs12046466 CAPZA1 Intronic 22,824 2.36E−12
1p33 47980916 rs6658111 FOXD2 Intergenic 22,824 3.85E−11
11q22.3 104012656 rs1681464 PDGFD Intronic 22,824 7.51E−11
6q22.32 127096181 rs9401907 RSPO3 Intergenic 22,824 2.11E−10
7p21.1 18904400 rs12700001 HDAC9 Intronic 22,824 2.12E−10
5q12.1 60315823 rs10939879 NDUFAF2 Intronic 22,824 2.92E−10
Caudal anterior cingulate 5q14.3 82852578 rs309588 VCAN Intronic 22,748 2.60E−10
Insula 11q23.1 110949402 rs321403 C11orf53 Intergenic 22,543 9.58E−12
8q24.12 120596023 rs10283100 ENPP2 Exonic 21,481 8.29E−11