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. Author manuscript; available in PMC: 2021 Oct 1.
Published in final edited form as: J Pineal Res. 2020 Jul 19;69(3):e12675. doi: 10.1111/jpi.12675

Figure 1:

Figure 1:

DLMO for the Baependi population (mean is marked with red dotted line) compared with published DLMO data from other adult populations9,2830,32,3542. Data are presented as mean±SEM. Different methodologies for determining DLMO are shown as follows: Dynamic threshold refers to defining DLMO based on two standard deviations above the mean of three or more pre-rise values or from parameters describing a fitted curve to the time series of melatonin samples. Fixed threshold refers to analyzing DLMO based on a time of attaining a 1 or 3 pg/ml level for saliva or a comparable 10 pg/ml for plasma. The threshold used in the present study was 3 pg/ml.