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. 2020 Sep 22;11:4779. doi: 10.1038/s41467-020-18618-y

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — Heatmaps of myeloid and lymphoid significance P values, as derived from CellDMC, in five separate cohorts and for a panel of seven CpGs which Su et al. showed to exhibit myeloid and lymphoid specific hypomethylation in smokers. The first four cohorts are whole blood samples. Significance of P values is denoted by color, and the corresponding t-test statistic values are displayed in the heatmap. P values derive from the t-test in the CellDMC model and are two-tailed.