Table 3.
Multivariable Cox Proportional Hazards Regression Analysesa of Factors Associated With Incidence of the First Self-Harmb in the Cohort: Overall and by TF/TM Status (N=6,327)
| Participant characteristics | Overall cohort HR (95% CI) |
TF cohort HR (95% CI) |
TM cohort HR (95% CI) |
|---|---|---|---|
| TF/TM status | |||
| TF | 1.00 (ref) | NA | NA |
| TM | 0.95 (0.73, 1.22) | NA | NA |
| Age at index date, years | |||
| >45 | 1.00 (ref) | 1.00 (ref) | 1.00 (ref) |
| 36–45 | 3.26 (1.77, 6.00) | 4.83 (2.34, 9.94) | 1.56 (0.51, 4.80) |
| 26–35 | 2.82 (1.53, 5.20) | 3.65 (1.69, 7.88) | 2.09 (0.76, 5.71) |
| 18–25 | 3.25 (1.84, 5.75) | 3.76 (1.79, 7.89) | 2.57 (1.01, 6.55) |
| 3–17 | 7.33 (4.32, 12.43) | 6.84 (3.49, 13.41) | 6.70 (2.76, 16.28) |
| Number of mental health diagnoses at baselinec | |||
| None | 1.00 (ref) | 1.00 (ref) | 1.00 (ref) |
| 1–2 | 2.34 (1.65, 3.32) | 2.13 (1.34, 3.40) | 2.66 (1.55, 4.56) |
| >2 | 3.68 (2.47, 5.48) | 3.05 (1.78, 5.22) | 4.64 (2.53, 8.52) |
| History of suicidal ideation or self-harm at baselinec | |||
| No | 1.00 (ref) | 1.00 (ref) | 1.00 (ref) |
| Yes | 3.62 (2.58, 5.08) | 4.61 (2.75, 7.74) | 3.01 (1.94, 4.69) |
a
Stratified on race/ethnicity and study site (KPNC vs Other).
b
Includes any diagnosis of self-inflicted injury, possibly self-inflicted injury, and self-inflicted injury/poisoning.
c
Baseline refers to diagnoses that occurred on or before index date.
TF, transfeminine; TM, transmasculine; HR, hazard ratio; NA, not applicable.