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. 2020 Sep 22;10:15413. doi: 10.1038/s41598-020-72348-1

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Colour map of metabolites originating from [U-¹³C] glucose measured in ¹H-¹³C-HSQC NMR spectra as mean of n = 3 replica. (A) For each metabolite, the ratio of concentrations between determinations after 8 h and 2 h incubation is shown. (B) For each metabolite, the ratio between 35 mM and 11.7 mM glucose is shown. Individual ratios with standard deviation are given in Fig S3.