Table 1b.
Cox regression analyses for overall survival in the total analysis population, showing hazard ratios for CDK4/6i + ET versus ET.
| Setting | Unadjusted analysis |
Adjusted analysis a |
||
|---|---|---|---|---|
| HR (95% CI) | P value | HR (95% CI) | P value | |
| First line | 0.91 (0.42, 1.98) | 0.82 | 0.98 (0.45, 2.13) | 0.95 |
| Second line | 0.80 (0.41, 1.55) | 0.50 | 0.83 (0.43, 1.63) | 0.59 |
| Third line | 1.57 (0.75, 3.29) | 0.23 | 1.69 (0.79, 3.62) | 0.18 |
CDK4/6i, CDK4/6 inhibitor; CI, confidence interval; ET, endocrine therapy; HR, hazard ratio.
a
HRs are adjusted for age and grade.