Figure 10.

(A) Scanning electron micrograph of the midsegment of a 4 mm ePTFE graft, in-vitro enothelilised with mass-cultured, allogenic, multidonor endothelial cells after 16 days of implantation as femoral graft in a senescent Chacma Baboon. Only residual cell islands are left of an originally confluent endothelium at the time of implantation interspersed with denuded areas with densely adherent leukocytes and platelets. (B) Confluent monolayer of autologous endothelial cells 4 weeks after implantation of an in vitro endothelialised 4-mm ePTFE femoro-femoral graft into a senescent baboon. One can still recognize the underlying structure of the PTFE graft. No endothelial cell detachment was found in spite of the shear stress exposure. The antithrombogenic potential of the cultured endothelial cells was reflected by a higher patency rate and the lack of platelet or fibrin depositions. With permission from (208) and (209).