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. 2020 Sep 9;10:543562. doi: 10.3389/fonc.2020.543562

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Copyright © 2020 Zheng, Zhou, Qu, Ren, Yan, Guo and Yue.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Potential mechanisms that underlie the VEGFR2 associations with metastasis and survival time. (A) VEGFR2-related genes, HUVOS grade and overall survival were analyzed by heat map observation and cluster analysis. (B) Differentially expressed genes were analyzed by visual analysis of heat maps in the VEGFR2 high- and low-expression groups. (C,D) Differentially expressed VEGFR2-related genes were investigated by analysis of the gene annotation network and GSEA.