Table 3.

Multivariate analysis of the association of the timing of antibiotics administration with PICU mortality.

	Variable	AOR	95% CI	p
All patients	1-h delay	1.205	0.379–3.833	0.752
	2-h delay	1.208	0.550–2.651	0.638
	3-h delay	1.798	0.800–4.042	0.156
Septic shock	1-h delay	5.144	0.534–49.544	0.156
	2-h delay	2.181	0.632–7.532	0.217
	3-h delay	3.852	1.032–14.374	0.045
Severe sepsis	1-h delay	0.613	0.149–2.515	0.497
	2-h delay	0.973	0.320–2.961	0.962
	3-h delay	1.365	0.433–4.302	0.595

Adjusted variables: PIM 3 score, age, comorbidities, and volume of resuscitation in the first 2 h. AOR, adjusted odds ratio; CI, confidence interval; PICU, pediatric intensive care unit.