Table 4.

Multivariate linear regression for PICU LOS, hospital LOS, and VFD.

Antibiotics within 1 h	Effect on increasing/decreasing duration
	PICU LOS			Hospital LOS			VFD
	Effect size	95% CI	P	Effect size	95% CI	p	Effect size	95% CI	p
All patients	−0.055	−0.261 to 0.151	0.598	0.010	−0.139 to 0.160	0.892	0.021	−0.036 to 0.079	0.468
Septic shock	0.314	0.020 to 0.603	0.037	0.159	−0.099 to 0.417	0.223	0.026	−0.105 to 0.158	0.685
Severe sepsis	−0.328	−0.607 to −0.049	0.022	−0.074	−0.257 to 0.108	0.422	0.032	−0.016 to 0.080	0.190

Adjusted variables: PIM 3 score, age, comorbidities, volume resuscitation in the first 2 h. VFD, ventilation-free days; LOS, length of stay; PICU, pediatric intensive care unit; CI, confidence interval.