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. 2020 Sep 9;11:778. doi: 10.3389/fgene.2020.00778

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Copyright © 2020 Zhang, Xiang, He, Liang, Wang, Luo and Zheng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Relative expression, methylation, and ROC of top hub genes from 4 DEMGs subgroups. Expression level in 30 CAD patients and 30 controls. (A) FN1. (B) PTEN. (C) POLR3A. (D) UBR1. Methylation levels in 30 CAD patients and 30 controls. (E) FN1. (F) PTEN. (G) POLR3A. Correlation between expression and methylation. (H) FN1. (I) PTEN. (J) POLR3A. ROC is based on expression and methylation separately or combined. (K) FN1. (L) PTEN. (M) POLR3A. All experiments were performed twice. *P < 0.05, **P < 0.01, ***P < 0.001.