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. 2020 Sep 9;11:778. doi: 10.3389/fgene.2020.00778

TABLE 1.

Clinical characteristics of subjects in validation study.

Characteristic Controls CAD patients P value
Demographics
Male/Female 17/13 22/8 0.2789
Age (year) 55.27 ± 9.03 59.80 ± 9.26 0.0598
Risk factors
History of HP (yes/no) 9/21 20/10 0.0092
History of DM (yes/no) 1/29 8/22 0.0257
Clinical parameters
TC (mmol/L) 4.25 ± 0.72 4.53 ± 1.45 0.3429
TG (mmol/L) 1.14 ± 0.39 1.89 ± 1.43 <0.001
LDL-C (mmol/L) 2.60 ± 0.60 2.80 ± 1.08 0.3701
HDL-C (mmol/L) 1.41 ± 0.34 1.30 ± 0.47 0.2964
FPG (mmol/L) 5.48 (5.03, 5.73) 5.69 (5.18, 6.90) 0.0740
WBC (× 109) 5.84 ± 1.33 6.33 ± 1.77 0.2290
Monocyte (× 109) 0.43 ± 0.11 0.58 ± 0.21 <0.001
Neutrophil (× 109) 3.31 ± 1.03 3.97 ± 1.28 0.0315
Lymphocyte (× 109) 1.93 ± 0.51 1.60 ± 0.61 0.0250
LMR (ratio) 4.68 ± 1.17 2.98 ± 1.21 <0.001
NMR (ratio) 7.70 (6.13, 8.85) 6.48 (5.53, 8.90) 0.1973
NLR (ratio) 1.68 (1.30, 2.05) 2.58 (1.94, 3.20) <0.001

Data were showed as mean ± SD, median (25 percentiles, 75 percentiles). HP, hypertension; DM, diabetes mellitus; TC, total cholesterol; TG, triglycerides; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; FPG, fasting plasma glucose; WBC, white blood cell; LMR, lymphocyte to monocyte ratio; NMR, neutrophil to monocyte ratio; NLR, neutrophil to lymphocyte ratio. Entries in bold font indicate statistically significant (P < 0.05).