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. 2020 Jul 20;319(3):G333–G344. doi: 10.1152/ajpgi.00150.2019

Fig. 5.

Fig. 5.

Sulfatase 2 (SULF2) knockout (KO) decreases fast-food diet (FFD)-induced liver inflammation. A: serum alanine aminotransferase (ALT) levels in wild-type (WT) and Sulf2-KO mice on standard chow diet (SC) or FFD. RT-PCR of hepatic mRNA expression of TNFR1 (B), IL6R (C), IL1βR1 (D), and osteopontin (E) in WT and Sulf2-KO mice fed SC or FFD. The mRNA expression of each gene was normalized to 18s rRNA. Histological assessment of inflammation (F), ballooning (G), and steatosis (H) in WT vs. Sulf2-KO mice fed SC or FFD in hematoxylin and eosin-stained liver sections. Data shown represent 9–12 mice per group.