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TGFβR2- and PDGFRβ1-target genes are downregulated by sulfatase 2 (SULF2) knockout. Hepatic mRNA expression levels of Collagen 1α1 (A), TIMP1 (B), and α-SMA (C) were determined by quantitative RT-PCR in wild-type (WT) and Sulf2-KO mice on standard chow diet (SC) or fast-food diet (FFD) and normalized to 18s rRNA. Data were further subcategorized by sex and analyzed. Data shown represent 9–12 mice per group or 5 or 6 mice per group when subcategorized by sex.
