. 2020 Aug 5;319(3):G345–G360. doi: 10.1152/ajpgi.00055.2020

Table 1.

Circulating serum levels of lipids

	16 wk		25 wk		37 wk		52 wk
	NC	ALIOS	NC	ALIOS	NC	ALIOS	NC	ALIOS
Males, mmol/L
Total cholesterol	2.6 ± 0.1	3.9 ± 0.2^‡	2.1 ± 0.1	4.1 ± 0.2^§	2.4 ± 0.1	4.6 ± 0.3^§	2.5 ± 0.2	5.8 ± 0.4^§
HDL	1.8 ± 0.1	2.7 ± 0.1^§	1.5 ± 0.1	2.9 ± 0.1^§	1.7 ± 0.1	3.1 ± 0.2^§	1.7 ± 0.1	3.7 ± 0.4^§
LDL	0.59 ± 0.02	0.9 ± 0.1^‡	0.43 ± 0.03	0.9 ± 0.1^§	0.6 ± 0.1	1.3 ± 0.2^§	0.5 ± 0.1	1.8 ± 0.2^§
TAG	1.1 ± 0.1	1.2 ± 0.1	1.0 ± 0.1	1.0 ± 0.1	1.3 ± 0.1	1.1 ± 0.1	0.94 ± 0.04	0.67 ± 0.04^§
Free fatty acids	1.7 ± 0.1	1.5 ± 0.1	0.9 ± 0.1	0.81 ± 0.05	1.9 ± 0.1	1.8 ± 0.1	0.8 ± 0.1	0.67 ± 0.04^*
Females, mmol/L
Total cholesterol	2.0 ± 0.1	2.4 ± 0.2^*	2.0 ± 0.1	2.8 ± 0.2^‡	1.7 ± 0.1	2.9 ± 0.2^‡	1.7 ± 0.1	3.2 ± 0.4^‡
HDL	1.3 ± 0.1	1.5 ± 0.1	1.4 ± 0.1	2.0 ± 0.1^‡	1.2 ± 0.1	2.1 ± 0.1^‡	1.2 ± 0.1	2.1 ± 0.2^‡
LDL	0.48 ± 0.03	0.57 ± 0.04	0.45 ± 0.02	0.61 ± 0.04^‡	0.43 ± 0.01	0.71 ± 0.08^†	0.36 ± 0.02	0.74 ± 0.13^‡
TAG	0.8 ± 0.1	1.0 ± 0.1	0.65 ± 0.03	0.55 ± 0.02^*	0.97 ± 0.02	0.71 ± 0.04^‡	0.81 ± 0.03	0.55 ± 0.03^†
Free fatty acids	1.7 ± 0.1	1.7 ± 0.1	0.81 ± 0.04	0.64 ± 0.04^†	1.95 ± 0.15	1.37 ± 0.07^‡	0.97 ± 0.06	0.69 ± 0.04^†

Values are means ± SE. n = 12–15 Mice in each group. ALIOS, American lifestyle-induced obesity syndrome; TAG, triacylglycerol. Significantly different from normal chow (NC) at same age,

P < 0.05,

^†

P < 0.01,

^‡

P < 0.001, and

^§

P < 0.0001.