Tubular fluid solute concentrations (A–G), pH (H), and osmolality (I) along the superficial nephrons of male and female rat models. Tubular fluid solute concentrations are similar in the two sexes along the proximal segments but diverge downstream of the thick ascending limbs. Concentration profiles along the juxtamedullary nephrons are similar to the corresponding superficial nephrons. PT, proximal tubule; SDL, short descending limb; LDL, thin descending limb; LAL, thin ascending limb; TAL, thick ascending limb; DCT, distal convoluted tubule; CNT, connecting tubule; CD, collecting duct; TA, titratable acid. Brackets denote concentration.