Table 4.

Densitometry analysis of SNAT3 and the enzyme-to-actin ratio expressed as a percentage of vehicle or control

	SNAT3		Phosphate-Dependent Glutaminase	Glutamate Dehydrogenase	Glutamine Synthetase
	60 kDa	50 kDa
Vehicle/control, 6 days	100 ± 15	100 ± 20	100 ± 13	100 ± 8	100 ± 7
6 days of ACTZ	193 ± 17a	120 ± 9	96 ± 7	89 ± 9	64 ± 10a
6 days of acidosis	2,687 ± 462b	4,729 ± 265b	582 ± 84c	210 ± 17d	121 ± 5d
Vehicle/control, 2 wk	100 ± 12	100 ± 7	100 ± 10	100 ± 9	100 ± 7
2 wk of ACTZ	118 ± 14	107 ± 16	147 ± 11e	126 ± 6f	100 ± 8
2 wk of acidosis	293 ± 60g	483 ± 57g	394 ± 29g	157 ± 16	91 ± 8

Data are means ± SE; n = 10 rats for pooled vehicle and control groups for each time period and n = 5 rats for other groups. Data are also shown in Figs. 4 and 5.

^aP < 0.03 vs. vehicle/control;

^bP < 0.001 vs. 6 days of acetazolamide (ACTZ) treatment;

^cP < 0.02 vs. 6 days of ACTZ treatment;

^dP < 0.05 vs. 6 days of ACTZ treatment;

^eP < 0.02 vs. 2 wk of vehicle/control treatment;

^fP < 0.05 vs. 2 wk of vehicle/control treatment;

^gP < 0.05 vs. 2 wk of ACTZ treatment. One-way ANOVA was used for comparison between groups.