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. 2020 Jul 14;106(19):1483–1488. doi: 10.1136/heartjnl-2020-316706

Table 2.

Study quality domains by study design using the Newcastle-Ottawa Scale

High quality (%)
(score >6)
Medium quality (%)
(score 5–6)
Low quality (%)
(score <5)
Mean score
(maximum 9)
Study design
 All (n=17) 76.5 17.6 5.9 6.9 (1.2)
 Cohort (n=11) 81.8 9.1 9.1 7.2 (0.9)
 Case-control (n=6) 66.7 16.7 16.7 6.3 (1.5)
Selection
(maximum 4)
Comparability
(maximum 2)
Outcome or exposure
(maximum 3)
Mean total score
(maximum 9)
Study design
 Cohort 2.6 (0.7) 2 (0) 2.5 (0.7) 7.2 (0.9)
 Case-control 2.5 (1.2) 1.8 (0.4) 2 (0) 6.3 (1.5)
Year of publication
 1999 or earlier 2 (0) 2 (0) 3 (0) 7 (0)
 2000–2009 2.25 (0.5) 2 (0) 2.5 (0.6) 6.8 (0.5)
 2010 or later 2.8 (1.0) 1.9 (0.3) 2.2 (0.6) 6.9 (1.4)

The mean with SD in brackets is shown where applicable.