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. 2020 May 18;106(19):1495–1502. doi: 10.1136/heartjnl-2019-316118

Table 5.

Adjusted HRs for adverse events using competing risk regression

Characteristics Model 1:
unadjusted
HR (95% CI)
P value Model 2:
adjusted
HR* (95% CI)
P value Model 3:
adjusted
HR† (95% CI)
P value
MACCE (cardiovascular mortality, non-fatal myocardial infarction, non-fatal stroke, unplanned revascularisation) 1.69 (1.18 to 2.43) 0.004 1.65 (1.12 to 2.43) 0.012 1.57 (1.09 to 2.25) 0.015
Cardiovascular mortality 2.03 (0.99 to 4.18) 0.055 2.02 (0.96 to 4.25) 0.063 1.73 (0.82 to 3.61) 0.150
Non-fatal myocardial infarction 1.22 (0.67 to 2.24) 0.520 1.26 (0.64 to 2.46) 0.500 1.13 (0.63 to 2.04) 0.690
Non-fatal stroke 1.49 (0.85 to 2.62) 0.170 1.45 (0.80 to 2.62) 0.220 1.33 (0.76 to 2.35) 0.320
Unplanned revascularisation 1.27 (0.66 to 2.45) 0.470 1.27 (0.64 to 2.52) 0.500 1.28 (0.67 to 2.46) 0.450
All-cause mortality 1.81 (1.06 to 3.09) 0.030 1.78 (1.01 to 3.14) 0.045 1.35 (0.77 to 2.36) 0.300
Sudden cardiac death or resuscitated cardiac arrest 2.51 (1.11 to 5.71) 0.028 2.41 (0.99 to 5.87) 0.052 2.09 (0.91 to 4.85) 0.084
Heart failure hospitalisation 2.22 (1.39 to 3.53) <0.001 2.11 (1.32 to 3.38) 0.002 1.78 (1.07 to 2.96) 0.026
New-onset atrial fibrillation 1.16 (0.88 to 1.54) 0.300 1.15 (0.86 to 1.54) 0.340 1.15 (0.86 to 1.53) 0.340

*Model 2: competing risk regression adjusted for age, sex, body mass index and smoking status with backward selection method.

†Model 3: Competing risk regression adjusted for age, sex, body mass index, smoking status, number of bypass grafts, left ventricular ejection fraction, diabetes mellitus, hypertension, chronic kidney disease and excessive daytime sleepiness with backward selection method.

MACCE, major adverse cardiac and cerebrovascular events.