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. 2020 Sep 4;11:1775. doi: 10.3389/fimmu.2020.01775

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Copyright © 2020 Vardi, Chermesh, Werner, Barel, Freund, McCourt, Fisher, Pinsker, Javasky, Weiss, Rechavi, Hagin, Snapper, Somech, Konnikova and Shouval.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Aberrant Treg phenotype in the LRBA-deficient patient. Figure depicts (A) decreased percentages of CD25^highFOXP3⁺ Tregs, (B) decreased levels of helios⁺ inducible Tregs, and (C) low levels of CTLA4 in Tregs in the LRBA-deficient patient, compared with control. Cells gated on CD4⁺ T cells.