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Decreased cytokine production by the LRBA-deficient patient. (A) Ratio of memory T cells producing TNF-α to those not producing any TNF-α, without stimulation. (B) Heatmap of cytokine expression under baseline conditions and with PMA/I stimulation in clusters associated with Figure 3B. PMA/I, phorbol 12-myristate 13-acetate and ionomycin.
