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. 2020 Sep 18;13:351–368. doi: 10.2147/CEG.S262879

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© 2020 Longo et al.

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(A) Determination of body weight parameters (p <0.001): a significant difference between groups is observed starting in the sixth week. * significant effect of the high-fat and choline-deficient diet according generalized estimating equations (GEE) followed by Bonferroni’s test. (B) Delta Lee index, *significant effect of the high-fat and choline-deficient diet (p = 0.017). Data expressed as mean ± standard deviation, Student’s t-test. Each experimental group with 10 male Sprague Dawley rats.