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miRNAs in Treg-cell development and function. Among others, three miRNAs play critical roles in these processes, miR-181a/b-1, miR-155 and miR-17∼92. Whereas miR-181 exerts its function predominantly during intrathymic tTreg-development, miR-155 and miR-17∼92 control Treg-cell homeostasis and function. Of note, the role of miR-17∼92 promoting or limiting Treg-cell function remains unclear (indicated by a question mark).
