Figure 3.
Effects of RAB31 silencing in OS migration and invasion. (A) Silencing of RAB31 expression significantly inhibited the migration of MG63 and (B) U2OS cells compared with the NC siRNA groups. (C) Representative images and (D) quantification showing that silencing of RAB31 significantly inhibited the invasion of MG63 and U2OS cells compared with the NC siRNA groups. Data are presented as the mean ± standard deviation. **P<0.01 vs. NC siRNA. RAB31, Ras-related protein Rab-31; siRNA, small interfering RNA; NC, negative control. Magnification for cell migration ×40 and for cell invasion ×400.