Table I.

Association between RAB31 expression and clinicopathological characteristics of patients with osteosarcoma.

Characteristic	Cases (n=54)	Low RAB31 expression (n=33)	High RAB31 expression (n=21)	P-value
Age, years				0.784
<20	22	14	8
≥20	32	19	13
Sex				0.575
Male	33	19	14
Female	21	14	7
Tumor size, cm				0.092
<8	24	18	6
≥8	30	15	15
Location				0.772
Femur or tibia	37	22	15
Other	17	11	6
Lung metastasis				0.001a
No	38	29	9
Yes	16	4	12
TNM stage				0.018a
I/IIA	19	16	3
IIB/III	35	17	18
Serum lactate dehydrogenase				0.151
Normal	20	15	5
Elevated	34	18	16
Serum alkaline phosphatase				0.168
Normal	22	16	6
Elevated	32	17	15

^aStatistically significant. RAB31, ras-related protein Rab-31; TNM, tumor-node-metastatsis.