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Chitotriosidase (CHIT1) and cell type specificity and its role in associated pathological disorders. CHIT1 is the first mammalian chitinase to be discovered and characterized. It is a potential biomarker of activated macrophages in tissues hence exhibits a significant role in the manifestation of both innate and adaptive immunity. It exhibits hydrolysis as well as trans-glycosylation as its chitinolytic activity.
