Table 1.
Physical characterization of sorafenib entrapped sodium selenite nanoparticles formulated by using various techniques.
|
Chemical Cross
Linking Agents |
Strength
(% v/v or w/v) |
Zeta Potential (mV) | PDI |
% Poly
Dispersity |
Zeta Average Size (d.nm) | SEM Studies Size (nm/µm) |
Mobility
mS/cm |
%Mass (r.nm) |
|---|---|---|---|---|---|---|---|---|
| Cross linking method | ||||||||
| Formaldehyde | 0.5 | 1.43 | 0.732 | 85.5 | 202.4 | 280 | 5.55 | 1.9 |
| Magnesium sulfate | 0.5 | -19.4 | 0.513 | 71.6 | 456.4 | 520 | 23.5 | 33 |
| Tripolyphosphate | 0.5 | -20.1 | 0.342 | 88.7 | 189 | 210 | 23.8 | 46.5 |
| Dextran Sulfate | 0.5 | -8.7 | 0.565 | 75.2 | 796.4 | 930 | 14.1 | 5.2 |
| Aluminium hydroxide | 0.5 | 2.72 | 0.731 | 85.5 | 209.5 | 270 | 8.51 | 3.3 |
| Solvent evaporation method (Ideal batch) | ||||||||
| Tripolyphosphate | 0.5 | –37.5 | 0.414 | 66.4 | 391.9 | 456 | 33.5 | 44.6 |