Table 3.

Univariate and Multivariate Cox Regression Models to Identify Predictors for appropriate ICD therapy in All Patients

Variable	Univariate Analysis			Multivariate Analysis
	HR	95% CI	P Value	HR	95% CI	P Value
Age	0.99	0.98–1.00	0.08
Female	0.41	0.29–0.59	< 0.001	0.45	0.27–0.75	0.002
Primary prevention	0.54	0.40–0.72	< 0.001	0.28	0.10–0.83	0.02
Hypertension	1.04	0.81–1.32	0.78
Diabetes mellitus	1.01	0.78–1.32	0.92
Chronic kidney disease	1.24	0.94–1.63	0.13
Hyperlipidemia	1.09	0.86–1.39	0.48
Atrial fibrillation	1.20	0.94–1.53	0.14
ICM	1.13	0.89–1.44	0.32
LBBB	0.67	0.52–0.85	0.001	0.72	0.50–1.05	0.08
QRS duration	0.997	0.992–1.001	0.17
NYHA functional class	1.16	0.91–1.47	0.24
LVEF	0.98	0.96–1.00	0.02	0.97	0.95–1.01	0.11
TRT	0.97	0.71–1.32	0.84
Statin	1.02	0.80–1.30	0.87
amiodarone	1.62	1.22–2.15	0.001	0.44	0.16–1.27	0.13
Digoxin	1.55	1.22–1.97	< 0.001	1.44	1.00–2.07	0.05
ACEARB	0.77	0.57–1.05	0.09	0.73	0.45–1.18	0.20
Aldactone	1.07	0.82–1.38	0.62
Furosemide	1.30	0.99–1.71	0.06	1.13	0.75–1.70	0.54
CRT response	0.43	0.32–0.59	< 0.001	0.46	0.32–0.68	< 0.001
TSH per 5 mIU/L	1.05	1.02–1.09	0.002	1.23	1.01–1.50	0.04

Abbreviations as in Table 1. TSH thyroid-stimulating hormone