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. Author manuscript; available in PMC: 2020 Sep 23.
Published in final edited form as: Biochemistry. 2020 Aug 30;59(36):3300–3315. doi: 10.1021/acs.biochem.0c00608

Figure 6: Inhibition of TrxR enzymes by acrolein.

Figure 6:

(A) Inhibition of mTrxR-CUG (WT) and mTrxR-C(αMe)UG (mutant) by acrolein after 10 min incubation in 100 mM potassium phosphate, 1 mM EDTA, pH 7 buffer at 22 °C. (B) Inhibition of DmTrxR-CCS by acrolein using the same conditions as mTrxR inhibition described in (A). The error bars represent the standard deviation of three trials.