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. Author manuscript; available in PMC: 2020 Sep 23.
Published in final edited form as: Biochemistry. 2020 Aug 30;59(36):3300–3315. doi: 10.1021/acs.biochem.0c00608

Table 5:

Half maximal inhibitory concentration (IC50) of RES for TrxR enzymes.

RES mTrxR-CUG mTrxR-C(αMe)UG DmTrxR-CCS
Curcumin 34 μM > 200 μM -
Cinnamaldehyde 225 μM 230 μM -
4-Hydroxynonenal 235 μM 118 μM -
Acrolein 231 nM 57 nM 7 μM