Table 5.
Area under the curve for diagnosis of mucinous and malignant cysts
Variables |
Mucinous cysts |
Malignant cysts |
||||||
AUC | P value |
Confidence interval |
AUC | P value |
Confidence interval |
|||
Lower limit | Upper limit | Lower limit | Upper limit | |||||
CEA in mg/dL | 0.889 | 0.002 | 0.720 | 1.000 | 0.812 | 0.038 | 0.579 | 1.000 |
Cytology | 0.598 | 0.443 | 0.349 | 0.847 | 0.771 | 0.072 | 0.571 | 0.970 |
Mutation (KRAS/GNAS) | 0.833 | 0.009 | 0.634 | 1.000 | 0.841 | 0.023 | 0.615 | 1.000 |
Met_NESP55 | 0.620 | 0.35 | 0.370 | 0.869 | 0.759 | 0.085 | 0.481 | 1.000 |
Met_AS | 0.590 | 0.483 | 0.339 | 0.841 | 0.741 | 0.108 | 0.461 | 1.000 |
Met_XL | 0.474 | 0.841 | 0.228 | 0.721 | 0.629 | 0.389 | 0.357 | 0.902 |
Met_1A | 0.513 | 0.92 | 0.262 | 0.764 | 0.565 | 0.667 | 0.261 | 0.868 |
GNAS locus methylation changes | 0.645 | 0.256 | 0.400 | 0.891 | 0.971 | 0.002 | 0.901 | 1.000 |
AUC: Area under the curve; CEA: Carcinoembryonic antigen; GNAS: Guanine nucleotide-binding protein, alpha stimulating; Met: Methylation changes.