Table 2.
Cohort III: main anthropometric and metabolic variables
| Variables | OGTT | IIGI | P value* |
|---|---|---|---|
| n (female/male) | 15 (11/4) | 15 (11/4) | — |
| Age (years) | 34 ± 12 | — | — |
| BMI (kg/m2) | 26.4 ± 1.9 | — | — |
| Waist (cm) | 86.9 ± 8.3 | — | — |
| Fat mass (%) | 30.7 ± 6.3 | — | — |
| Fasting glucose (mmol/L) | 5.3 ± 0.3 | 5.3 ± 0.4 | NS |
| 2 h glucose (mmol/L) | 6.8 ± 1.2 | 6.9 ± 1.0 | NS |
| HbA1c (%) | 5.1 ± 0.2 | — | — |
| HbA1c (mmol/mol) | 32.0 ± 0.7 | — | — |
| Total cholesterol (mmol/L) | 4.1 ± 0.9 | — | — |
| HDL cholesterol (mmol/L) | 1.4 ± 0.2 | — | — |
| LDL cholesterol (mmol/L) | 2.3 ± 0.7 | — | — |
| TGs (mmol/L) | 0.7 (0.6–1.0) | — | — |
| Fasting succinate (µmol/L) | 41.3 ± 14.4 | 42.1 ± 4.2 | NS |
| Fasting insulin (pmol/L) | 47.5 ± 17.5 | 43.1 ± 3.8 | NS |
| Fasting C-peptide (nmol/L) | 0.4 (0.3–0.4) | 0.3 (0.2–0.4) | NS |
| Fasting GLP-1 (pmol/L) | 26.8 ± 8.7 | 24.4 ± 2.2 | NS |
| TG index | 4.4 ± 0.1 | — | — |
| OGIS index (mL/min/m2) | 414.0 ± 53.8 | — | — |
| Insulinogenic index | 1.0 ± 0.4 | — | — |
Data are presented as mean ± SD or median (25th–75th percentiles), as appropriate. OGIS, oral glucose insulin sensitivity index.
*
P values for the normal distributed variables were calculated using paired t test; for the nonnormal distributed variables, Wilcoxon signed rank test was used.