Fig. 7.

ARCSP-induced autophagy has antitumor effects in vivo. a-b HeLa xenograft tumors in the control group and ARCSP-treated group were measured once a day for 25 days. a Body weight change. b Tumor volume change. c The final tumor weights were measured. d An image of a representative tumor is shown. e The levels of LC3B-II/I and Atg7 were detected by Western blotting. f Immunohistochemical staining with LC3B, Bax, Ki67 and PCNA antibodies in tumor tissue (shown as brown staining). Scale bar = 50 μm. The data are expressed as the mean ± SD; ^*P < 0.05, ^**P < 0.01, ^***P < 0.001. ns, not significant