Table 1.
Baseline characteristics of all patients (N = 137)
| Variable | No. (%) or median (IQR) |
|---|---|
| Age, yr | 64 (57, 72) |
| Sex | |
| Male | 83 (60.6%) |
| Female | 54 (39.4%) |
| BMI | 23.4 (22.0, 25.3) |
| ECOG Performance status | |
| 0 | 64 (46.7%) |
| ≥ 1 | 73 (53.3%) |
| Chronic hepatitis B | 21 (15.3%) |
| Chronic hepatitis C | 4 (2.9%) |
| Hepatolithiasis | 17 (12.4%) |
| Liver cirrhosis | 15 (10.9%) |
| Child-Pugh class A | 12 (8.8%) |
| Child-Pugh class B | 3 (2.2%) |
| Diabetes mellitus | 25 (18.2%) |
| Charlson Commorbidity Index | |
| 0 | 87 (63.5%) |
| ≥ 1 | 50 (36.5%) |
| Biliary drainage | 15 (10.9%) |
| Tumor size, cm | 7.0 (5.0, 9.9) |
| Major vascular invasion | 89 (65.0%) |
| Hilar invasion | 16 (11.7%) |
| Liver metastasis | 55 (40.1%) |
| Extrahepatic organ metastasis | 75 (54.7%) |
| Peritoneum | 35 (25.5%) |
| Lung | 33 (24.1%) |
| Bone | 25 (18.2%) |
| Distant lymph node metastasis | 90 (65.7%) |
| Number of metastatic sites | |
| 0 | 36 (26.3%) |
| 1 | 59 (43.1%) |
| ≥ 2 | 42 (30.7%) |
| Baseline laboratory findings | |
| White blood cell count, cells/μL | 8060 (6700, 9440) |
| Neutrophil count, cells/μL | 5606 (4126, 6751) |
| Lymphocyte count, cells/μL | 1612 (1346, 2029) |
| Monocyte count, cells/μL | 633 (509, 801) |
| Hemoglobin, g/dL | 12.6 ± 1.7 |
| Platelet count, 103 cells/μL | 237 (185, 281) |
| Albumin, g/dL | 4.0 (3.6, 4.2) |
| Globulin, g/dL | 3.2 (3.0, 3.6) |
| Total bilirubin, mg/dL | 0.7 (0.5, 0.9) |
| ALP, IU/L | 139 (98, 245) |
| AST, IU/L | 34 (24, 51) |
| ALT, IU/L | 26 (17, 44) |
| CA 19–9, U/mL | 266 (27, 4280) |
| Platelet-to-lymphocyte ratio | 133 (110, 186) |
| Neutrophil-to-lymphocyte ratio | 3.4 (2.3, 4.4) |
| Lymphocyte-to-monocyte ratio | 2.5 (2.1, 3.2) |
| Albumin-to-globulin ratio | 1.2 ± 0.3 |
Abbreviations: IQR Interquartile range; BMI Body mass index; ECOG Eastern Cooperative Oncology Group; ALP Alkaline phosphatase; AST Aspartate aminotransferase; ALT Alanine aminotransferase; CA 19–9 Carbohydrate antigen 19–9;
Data regarding hemoglobin and albumin-to-globulin ratio are presented as mean ± standard deviation