(A) Schematic of PB-SRT-tdTomato.
(B) Distribution of fluorescence intensity in K562 cells transfected with PB-SRT-tdTomato with and without piggyBac transposase.
(C) Neuron and astrocyte clusters from scRNA-seq analysis of mouse cortex libraries transduced with AAV-HyPBase and AAV-PB-SRT-tdTomato.
(D) Browser view of scCC HyPBase peaks in astrocytes and neurons alongside whole-cortex H3K27ac ChIP-seq.
(E) Expression specificity distributions ofgenes overlapping astrocyte or neuron peaks; horizontal lines indicate medians of the distributions. See also Figure S7. TR, terminal repeat; Rz, ribozyme.