Table 3.

Classification and genotypes of newborn infants with activity ≤40% of the days mean.

Pat	Class	G6PD-Activity 1	Nucleotide Change	Predicted Effect on Protein
01	II	2%	c.[1360C>T];[0]	p.[(Arg454Cys)];[0] 6
02	II	4%	c.[563C>T];[0]	p.[(Ser188Phe)];[0]
03	II	4%	c.[563C>T];[0]	p.[(Ser188Phe)];[0]
04	II	4%	c.[563C>T];[0]	p.[(Ser188Phe)];[0]
05	II	5%	c.[563C>T];[0]	p.[(Ser188Phe)];[0] 3
06	II	5%	c.[563C>T];[0]	p.[(Ser188Phe)];[0]
07	II	6%	c.[563C>T];[0]	p.[(Ser188Phe)];[0]
08	II	6%	c.[563C>T];[0]	p.[(Ser188Phe)];[0] 3
09	II	7%	c.[563C>T];[0]	p.[(Ser188Phe)];[0] 3,6
10	II	7%	c.[563C>T];[0]	p.[(Ser188Phe)];[0]
11	II	7%	c.[563C>T];[563C>T]	p.[(Ser188Phe)];[(Ser188Phe)] 2
12	II	8%	c.[563C>T];[0]	p.[(Ser188Phe)];[0]
13	II	8%	c.[267+5G>T];[563C>T]	p.[?];[(Ser188Phe)] 2,4,7
14	II	9%	N.D	p.[=];[0]
15	II	10%	c.[563C>T];[0]	p.[(Ser188Phe)];[0]
16	II	10%	c.[563C>T];[0]	p.[(Ser188Phe)];[0]
17	III	14%	c.[95A>G];[0]	p.[(His32Arg)];[0]6
18	III	14%	c.[871G>A];[0]	p.[(Val291Met)];[0]
19	III	18%	c.[406C>T;1048G>C];[0]	p.[(Arg136Cys;Asp350His)];[0]
20	III	20%	c.[376A>G;524A>T;968T>C];[376A>G]	p.[(Asn126Asp;Asp181Val;Leu323Pro)];[(Asn126Asp)] 2,5
21	III	22%	c.[871G>A];[0]	p.[(Val291Met)];[0]
22	III	22%	c.[202G>A;376A>G];[0]	p.[(Val68Met;Asn126Asp)];[0] 3
23	III	23%	c.[202G>A;376A>G];[0]	p.[(Val68Met;Asn126Asp)];[0] 3
24	III	24%	N.D	p.[=];[0] 3,6
25	III	25%	c.[376A>G;968T>C];[0]	p.[(Asn126Asp;Leu323Pro)];[0] 3
26	III	25%	c.[202G>A;376A>G];[202G>A;376A>G]	p.[(Val68Met;Asn126Asp)];[(Val68Met;Asn126Asp)] 2,5
27	III	36%	c.[202G>A;376A>G];[202G>A;376A>G]	p.[(Val68Met;Asn126Asp)];[(Val68Met;Asn126Asp)] 2,5
28	III	37%	c.[563C>T];[=]	p.[(Ser188Phe)];[=] 2
29	III	39%	N.D	p.[=];[0] 3,6

¹ Mean activity of 3 determinations, ² Girl, ³ Hemizygous for c.1311T>C, ⁴ Heterozygous for c.1311T>C, ⁵ Homozygous for c.1311T>C, ⁶ Hemizygous for c.1365-13C>T, ⁷ Heterozygous for c.1365-13C>T, Not detected, N.D.