Table 6.
AATD-COPD COHORT (CASES) | NON-AATD-COPD COHORT (CONTROLS) | |||
---|---|---|---|---|
N = 953 | N = 7,928 | |||
No. of patients | (Column %) / [median] | No. of patients | (Column %) / [median] | |
Age, mean (SD) | 56.24 (10.74) | [56] | 55.17 (9.62) | [56] |
Age categories, n (%) | ||||
30 - 39 | 57 | (6) | 445 | (6) |
40 - 49 | 191 | (20) | 1,697 | (20) |
50 - 59 | 355 | (37) | 3,194 | (37) |
60 - 64 | 174 | (18) | 1,537 | (18) |
>=65 | 176 | (18) | 1,055 | (18) |
Gender, n (%) | ||||
Male | 456 | (48) | 3,812 | (48) |
Female | 497 | (52) | 4,116 | (52) |
Race/Ethnicitya, n (%) | ||||
White | 877 | (92) | 7,526 | (95) |
African American | 39 | (4) | 201 | (3) |
Hispanic | 33 | (3) | 195 | (2) |
Census region, n (%) | ||||
Northeast | 104 | (11) | 104 | (11) |
Midwest | 287 | (30) | 287 | (30) |
South | 414 | (43) | 414 | (43) |
West | 148 | (16) | 148 | (16) |
Charlson Comorbidity Scorea, n (%) | ||||
1 | 596 | (63) | 5,416 | (68) |
2 | 161 | (17) | 1,282 | (16) |
3 | 90 | (9) | 592 | (7) |
4 | 40 | (4) | 207 | (3) |
≥5 | 66 | (7) | 431 | (5) |
aMissing race/ethnicity was replaced using multinomial logistic regression
bQuan's Enhanced Charlson Comorbidity Score calculated within 365 days before (including) the index date