Fig. 3.

Investigation of bacterial and fungal differential abundance among asthmatic individuals with relation to current medications and asthma control test (ACT). Differential abundance testing using DESeq2, R package to identify differentially abundant taxa among drug + ACT variables. The bar plot reports bacterial genera (a, b) and fungal genera (c, d) with significant abundance with relation to drug and ACT scores at a p-value < 0.05 and the Log2Fc / Fold Change > 1.5 or < − 1.5 for both bacterial and fungal genera. Controlled and uncontrolled ACT scores as well as steroid and steroid + LTRA current treatment corresponding abundance are colored in red and blue, respectively