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. Author manuscript; available in PMC: 2021 Aug 17.
Published in final edited form as: Chem Res Toxicol. 2020 Aug 4;33(8):2072–2086. doi: 10.1021/acs.chemrestox.0c00027

Scheme 1.

Scheme 1.

Pathway for Oxidation of DNA Involving Polyaromatic o-Quinones in the Presence of Cu2+ and NADPHa

aAdapted with permission from ref 15, copyright American Chemical Soc., 2005.